Targeted, better-tolerated oral PDE4 inhibitors are an unmet need in inflammatory bowel disease (IBD) PALI-2108 demonstrates in ex vivo studies; targeted activation and reduced side effects, ...

1 Division of Rheumatology, Department of Internal Medicine, School of Medicine, Keio University, Shinjuku-ku, Tokyo, Japan 2 Department of Medicine and Rheumatology, Graduate School of Tokyo Medical ...

Chromatin immunoprecipitation assay was used to analyse histone methylation within ... and further induced by tumour necrosis factor alpha through the nuclear factor kappa B and Jun kinase pathways.

Fasting serum insulin was measured using a chemiluminescence assay (Insulin Architect ... Interleukin 6 (IL-6) and tumour necrosis factor-alpha (TNFα) were measured by ELISA in plasma collected from ...

This is now possible with the development of reporter-gene assays that measure TNF-α-mediated effects on a TNF-receptor-positive human cell line. [78] This enables the detection of both TNF-α ...

The Minnesota Vikings will travel to sunny Southern California to take on the Los Angeles Rams in this Thursday Night Football showdown at 8:15 pm ET. The Minnesota Vikings had their first loss of ...

It would've been nice for things like bad coaching and putrid refereeing to not have gotten in the way, but the back-and-forth drama of this game was really fun to watch. This was an unbelievable ...

The Broncos got off to a hot start versus the Saints on Thursday night, heading into the locker room with a 16-3 lead at the half. Denver quarterback Bo Nix was prolific through the first two ...

This useful study examines the function of the rnc gene, which encodes the RNase III ribonuclease, as it relates to virulence of Salmonella Enteritidis. The authors demonstrate that the rnc gene is ...

Saints cornerback Paulson Adebo broke his femur in the team’s 33-10 loss to the Broncos on Thursday night, in which he was carted off in the first half and taken by ambulance to a New Orleans ...