Analysis from continued follow-up of Phase 1/2 clinical trial data in Hunter syndrome (MPS II) reinforces potential for tividenofusp alfa (DNL310) to address full disease spectrum Launch readiness ...

A new discovery by researchers from Adelaide University, in collaboration with Denmark’s Carlsberg Research Laboratory, will allow barley growers to optimise seed dormancy for their crops and improve ...

The inhibitor and substrate compete for the same binding site (or the active site) on the enzyme. The inhibitor decreases the enzyme’s capacity to bind the substrate, but this impact may be ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates - an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Using artificial intelligence, researchers show how γ-secretase recognizes substrates – an important advance for fundamental and translational research. The γ-secretase enzyme is capable of cleaving ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The translocation of DNA in polymerase (Pol) enzymes is a critical step for ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

This breakthrough not only converts methane—a potent greenhouse gas—into eco-friendly materials but also overcomes key industrial bottlenecks. (Representational image)Dr_Microbe Scientists are ...

Scientists have uncovered how certain genetic mutations lead to Alzheimer’s, not by producing toxic proteins, but by halting a crucial protein-processing mechanism. This stalled process may hold the ...

Alzheimer's disease is likely caused by stalled protein processing in the brain, according to a new study. For several decades, researchers studying Alzheimer's disease have been working to understand ...