Inspired by the simple mechanism of a seesaw—when one side goes up, the other side goes down—researchers asked an intriguing ...

This study reports an important and novel finding that TENT5A, an enzyme involved in fine-tuning poly(A) tail length on selected mRNAs, is required for proper enamel mineralization in mice. The ...

The inhibitor and substrate compete for the same binding site (or the active site) on the enzyme. The inhibitor decreases the enzyme’s capacity to bind the substrate, but this impact may be ...

ABSTRACT: Rhodanese plays a critical role in cyanide detoxification by catalyzing the conversion of toxic cyanide into the less harmful thiocyanate. This comprehensive review examines recent studies ...

CHAMPAIGN, Ill. — A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination ...

Abstract: Enzymes play a critical role in catalyzing biochemical reactions, and accurately predicting their substrate specificity is essential for applications in drug discovery, metabolic engineering ...

Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The translocation of DNA in polymerase (Pol) enzymes is a critical step for ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. In this study, we unveil a common mechanism underlying these ...

The Arctic air over the Great Lakes last week did cause a surge in ice concentration for most of the Great Lakes. Here’s a look at how the percentage of ice cover today compares to historical normals.

As you may know, there are four main types of enzyme inhibition: noncompetitive, uncompetitive, competitive, and mixed inhibition mechanisms. The similarity in their names makes it difficult and ...

Biochemical engineers want to transform the abundant and renewable wood into bioplastics, medically relevant chemicals, food additives, or fuel. However, the wood’s complex structure has been a major ...