and reverse signaling through ligation with transmembrane TNF. By blocking TNF, these agents may lead to serious adverse affects. Patients on anti-TNF therapy must be closely followed ...
Poster Presentation Title: A First-in-Human Phase 1a Randomized, Double-Blind Single-Ascending Dose Study of NAV-240, an anti-OX40L/TNF-alpha Bispecific ... and TNFα-driven signaling pathways ...
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