If all goes well this week at practice, McCaffrey will make his season debut Sunday against the Tampa Bay Buccaneers.

The newlyweds join George and Claire Kittle for a mountain getaway in a rare glimpse of the QB and his wife together.

Once this season is in the books, the San Francisco 49ers will likely set their sights on securing quarterback Brock Purdy with a long-term contract, potentially making him one of the highest-paid ...

Quarterback Lamar Jackson has enjoyed an excellent start to the season, and that continued against the Broncos for the ...

San Francisco 49ers quarterback Brock Purdy leans on a baseball influence to continue evolving his throwing motion.

After the Dallas Cowboys lost to the San Francisco 49ers yet again, SFGATE columnist Drew Magary has seen enough to declare ...

San Francisco 49ers rookie Dominick Puni has emerged as a reliable presence along the offensive line in his first NFL season.

Brock Purdy gave an interesting answer following the 49ers' win over the Cowboys that indicates he's placing too much ...

Despite dealing with a sprained foot that limited him in practice all week, TE George Kittle still managed to deliver a big ...

Brady and Belichick are getting along well with each other as both of them enter media, with Tom referring to Bill as ...

The Kansas City Chiefs own the San Francisco 49ers. Head coach Kyle Shanahan fell to 0-5 against the Chiefs and head coach ...