THE importance of the sodium ion in edema is well recognized. If a specific method were available for producing selective inhibition of the renal tubular reabsorption of sodium from the glomerular ...

Antibiotics are among the most frequently prescribed drugs in medicine. Their use, however, is often limited by associated renal toxic effects. The most common manifestation of these toxic effects is ...

Extract: This report concerns two patients with primary renal tubular acidosis (RTA) in whom the abnormality in hydrogen excretion was shown to result from inappropriate urinary loss of bicarbonate ...

This is the solution to a case we presented recently. You may review the case here. The patient had complained of dyspnea, and an abnormal electrolyte panel revealed a decreased bicarbonate level of ...

Renal drug excretion involves filtration, reabsorption, and secretion, crucial for drug clearance and minimizing toxicity. The study models renal clearance using pharmacokinetic parameters, validated ...

Phosphate, one of the most abundant anions in mammals, is crucial for bone mineralization and cellular activity. The kidney plays a central role in phosphate homeostasis. It adjusts urinary excretion ...