On the left, an unactivated RTK receptor (pink) encounters a ligand (red). Upon binding, the receptor forms a complex of proteins that phosphorylate each other. In turn, this phosphorylation affects ...
Macrophage colony stimulating factor (M-CSF), through binding to its receptor FMS, a class III receptor tyrosine kinase (RTK), regulates the development and function of mononuclear phagocytes, and ...
Growth factors stimulate receptor tyrosine kinases (RTK) which results in regulation of cell proliferation, growth, differentiation, and cell death. Therefore, RTKs are an attractive anti-cancer ...
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