Intracellular transport is a vital process that allows cells to move proteins and other molecules to specific locations. This ...

Precise intracellular transport is essential for neuronal function, yet the exact mechanism of selective cargo delivery by ...

How do neurons transport proteins? A new study reveals that Kinesin-2 motor subtypes regulate cargo specificity.

Cargo-adaptor binding to the KLC-TPR domains binding triggers structural rearrangements that relieve kinesin-1 autoinhibition, enabling MAP7 recruitment, through an allosteric mechanism that connects ...

The kinesin proteins (KIFs) are "cargo" proteins that transport vesicles, protein complexes, and RNA to specific destinations in a cell, but their direct involvement in more discrete activities such ...

Kinesin-2 motor proteins transport cargo along neuronal microtubules to ensure proper cellular organization. This study shows that kinesin-2 exists as distinct assemblies with different compositions ...

The puzzle of memory has intrigued philosophers and intellects for a very long time. Plato and Aristotle believed that memory was found only in the realm of the soul and the mind, but there was ...

Microtubules are protein fibers that facilitate the transport of cellular components throughout a cell’s interior. Within a cell, microtubules span from the nucleus to the cell membrane, and the motor ...