A total of 9% of placebo recipients contracted COVID-19 from a household member, compared with 2.9% of ensitrelvir recipients ...

The lack of available medications in the United States for COVID post-exposure prophylaxis leaves household members in close ...

The trial’s primary objective is to assess PALI-2108’s tolerability, pharmacokinetics and safety in healthy volunteers.

Proteases that are resident in, or released from, the endolysosomal system of leukocytes have important functions in the immune response. Lysosome-related organelles (LROs) or granules are the ...

The company discovered Serine Protease Inhibitors, a class of proteins, which quell inflammation, and Lauder will be researching the proteins’ applications in beauty, as well as other technologies, ...

Ensitrelvir PEP was safe and effective for COVID-19 prevention among household contacts when administered after the onset of symptoms in an index patient.

Integrase inhibitors stop the action of integrase ... PIs work by binding to the enzyme protease. HIV needs protease to replicate in the body. When protease can’t do its job, the virus can ...

Historically, most people started HIV treatment with two drugs from the NRTI class combined with either one NNRTI, one protease inhibitor or one integrase inhibitor – hence, ‘triple therapy’.

TB Alliance has disclosed new ATP-dependent Clp protease ClpP1P2 complex (Mycobacterium tuberculosis) inhibitors reported to be useful for the treatment of tuberculosis. BioWorld Science Infection ...