Phenylephrine is what’s known as a vasoconstrictor (meaning: it causes blood vessels to narrow), Dr. Parikh says. It works on ...

Phenylephrine itself is active as an alpha-1 adrenergic receptor agonist that can tackle the dilation of nasal blood vessels, which is a major feature of nasal congestion. However, its metabolites ...

In a separate session intravenous phenylephrine (200 μg) and l-methamphetamine (5 mg) were given to define alpha agonist pharmacology and bioavailability. Physiological, cardiovascular ...