Opioids slot into opioid receptors and activate them. This sends signals to your brain to relieve pain and promote pleasure. Both endogenous opioids, which your body naturally produces, and exogenous ...

Two different versions of the mu-opioid receptor within a cellular membrane illustrate how the receptor changes its conformation to send a signal into the cell. Scientists captured six high-resolution ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid receptors. What they didn't know—until now—was exactly what happens next.

Please provide your email address to receive an email when new articles are posted on . New data published in The New England Journal of Medicine showed that buprenorphine use during pregnancy was ...

A new study reveals the oligomeric molecular structure of the MOR-Gal1R complex, a component present in the brain which is involved in the analgesic and addictive effects of certain opioids. A study ...

Please provide your email address to receive an email when new articles are posted on . Gestational age at delivery was similar for naltrexone, buprenorphine and methadone. Naltrexone was associated ...

Researchers at USF Health have discovered a new way opioid receptors can work that may lead to safer pain medications. Their findings show that certain experimental compounds can amplify pain relief ...

Brandy Schillace’s review of “Candace Pert” by Pamela Rykman (Bookshelf, Nov. 15) contains a questionable conclusion: the discovery of the mu opioid receptor in 1972 “helped launch the opioid crisis” ...

Unbiased whole-brain mapping of c-Fos identifies active brain regions following a rewarding dose of oxycodone. c-Fos-positive cells are shown in red; white matter tracks are shown in green. Opioids, ...