A network meta-analysis reveals age-dependent variations in efficacy of popular diabetes drugs, with SGLT2 inhibitors showing ...

GLP-1 receptor agonists were more cardioprotective in younger people, but reduced HbA1c more with age. The age of type 2 ...

they want more data and may not trust SGLT2 inhibitors yet. Other HCPs want cardiologists to be leaders in this space, feeling that they should use these drugs in practice and share their ...

SGLT2 inhibitors and older GLP-1 drugs." The study's methodology involved using a target trial emulation, a type of study that "aims to mimic a randomized controlled trial," typically the gold ...

The researchers found that both SGLT2 inhibitors and GLP-1 agonists were associated with a lower risk of major cardiovascular events, but the drug effects varied with the patients’ age.

The widespread use of SGLT2 inhibitors alongside statins has raised concerns about potential drug interactions. Specifically, findings from a case report suggested a potential link between ...

To TCTMD, Wiviott said there is a large body of evidence supporting the SGLT2 inhibitor drug class, noting the medications have been a “remarkable advance in diabetes management and the prevention and ...

Objective Sodium–glucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ...

Adults with overweight or obesity and type 2 diabetes who are given the sodium glucose cotransporter 2 (SGLT-2) inhibitor drug dapagliflozin alongside moderate calorie restriction achieve much higher ...

SGLT2 inhibitors more cardioprotective in older versus younger people despite smaller reduction in HbA1c with older age ...

A meta-analysis, published in the Journal of the American Medical Association, has reviewed more than 600 trials to assess the efficacy of some of these medications. The researchers found that both ...