Authorities have reopened Interstate 45 near Crosstimbers following a deadly wrong-way crash involving four vehicles early ...

Monica Rosenda Valdez, 32, is accused of crashing a Ford F-150 into a Jeep on Interstate 45 and killing the vehicle's driver.

In other words, if ever you want to get the best lightning show in America, just drive about two-and-a-half hours north on Interstate 45 from Houston. Heck, maybe we should just rename the I-45 ...

Several lanes of Interstate Highway 45 North were closed early Thursday after a crash involving an 18-wheeler led to a hazmat ...

HPD investigators say the black Pontiac G6 exited the freeway at West Gulf Bank where he struck a curb and culvert and then rolled several times.

Police estimate the woman drove the wrong way on the North Freeway for about 10 to 15 minutes before the crash.

Drivers traveling north from Tiki Island must use the southbound entrance ramp to I-45, travel onto the island, take the Harborside Drive exit, U-turn at Harborside Drive and enter I-45. Once the ...

As snow falls through the region, PennDOT has implemented 45-mile-per-hour speed limits on all interstates in the Northwest PA region. While the speed restrictions are in place, commercial vehicles ...

Emergency responders were dispatched to a collision on Interstate 45 northbound at mile marker 177 in Buffalo on Thursday ...