TMCnet3d
Neurona Therapeutics Raises $102 Million to Fuel NRTX-1001 Phase 3 EPIC Epilepsy Trial and Advance Regenerative Cell Therapy Pipeline
The round recognizes recent FDA alignment to advance NRTX-1001 into the Phase 3 EPIC (EPIlepsy Cell therapy) trial - The Phase 3 EPIC trial is designed as a single pivotal trial and is intended to ...
Hosted on MSN11mon
Molecular atlas shows how the growth factor erythropoietin affects neurons
By analyzing about 12,000 transcriptomic single-cell nuclear data, the researchers were able to create a comprehensive molecular atlas of hippocampal interneurons and identify 15 interneuron subtypes.
Nature3mon
Bypassing interneurons: inhibition in neocortex
(a) In the 'classical' pathway, multiple pyramidal cells (for simplicity, only one pyramidal cell is shown: P 1) excite the inhibitory interneuron (I) at its soma. The interneuron then inhibits P ...
GEN18d
Gene Therapy Tested in Mice Offers New Hope for People with Dravet Syndrome
The paper is titled, “Interneuron-specific dual-AAV SCN1A gene ... encodes a sodium channel protein that is involved in brain cell signaling. This mutation leads to problems with interneurons ...