Ekberg and colleagues proposed that in type 1 diabetes a deficiency of C peptide, a subunit of the proinsulin molecule, also contributes to nerve damage; their animal studies showed that C-peptide ...

Tests confirmed that the transplanted E-islets were producing biologically relevant levels of insulin and c-peptide in response to meals. No tumors or serious adverse effects were observed.

The assessment of fetal and maternal B-cell function by C-peptide measurement requires an understanding of its metabolism in pregnancy. We gave 125 I-tyrosylated-C-peptide (I-CP) to 6 pregnant ...

Four weeks after transplantation, the study showed the survival and function of transplanted pancreatic beta cells, evidenced by circulating C-peptide levels, which indicate insulin production.