Did patients in a failed HIV vaccine trial halted in 2007 become more susceptible to the virus due to the adenoviral vector used to deliver the experimental vaccine? Researchers have speculated this ...

The VDL utilizes a vector construct that employs a nonhomologous viral envelope (derived from the vesicular stomatitis virus), possess only three HIV genes, and separates the genes encoding the ...

Among these, lentivirus-based vectors, derived from the HIV-1 retrovirus ... Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer ...

A new study led by Western researchers is the first to identify a factor that could influence how fast the pocket where human ...

This molecule, known as EBC-46, works by temporarily activating the HIV virus in the affected cells as they hide so that the body’s immune system can remove the virus, according to a study published ...

The virus' genome is incorporated ... finding techniques to shrink the vector. Using a more efficient Cas9, the team could inactivate the HIV genome with one guide sequence or completely extract ...

The strategy of minimizing the vector size was successful ... "We have developed an efficient combinatorial CRISPR-attack on the HIV virus in various cells and the locations where it can be ...

Figure 3: Restriction digestion of constructed full–length HIV–1 molecular ... transfected cells. No virus was detected from the control experiments using only vector plasmid DNA.