The use of GLP-1 receptor agonists corresponded with a lower risk for depression among older adults with type 2 diabetes ...

For older adults with type 2 diabetes (T2D), use of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) is associated with a modestly lower risk for depression compared with dipeptidyl peptidase-4 ...

1.36 ±0.05-fold [scrambled siRNA] expansion in 48 h; P < 0.05)(Fig. 5). Cyclin A2 knockdown completely inhibited exendin-4-induced proliferation stimulation in Min6 cells (Fig. 5). Lentiviral ...

This work confirmed that the lizard species' unique genes produce a protein, Exendin-4, that fit the bill, mimicking GLP-1 while hanging round in the human body for far longer. A synthetic version was ...