A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists at Martin Luther University Halle-Wittenberg (MLU) and TU Berlin have published ...

Usually enzyme complexes make multistep processes easier by catalyzing sequential reactions in which the product of one enzyme becomes the substrate for the next. In a new finding, researchers report ...

A new method has enabled the natural structure of particularly large and complex enzymes to be revealed. Scientists have investigated a multi-enzyme complex that plays an essential role in metabolism ...

A research team led by Wim Annaert (VIB-KU Leuven) uncovered the early assembly of gamma-secretase, a protein complex linked to numerous cellular processes including the development of Alzheimer's ...

Biological cells invest much of their resources into the production of enzymes, which catalyze the conversion of substrates into products. An international team of bioinformaticians and biophysicists ...

Researchers have used cryo- electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees ...

Researchers at the University of Basel have repurposed a natural enzyme so that it catalyzes a highly challenging chemical reaction. Their approach opens new possibilities for synthesizing complex ...

Nucleotide synthesis—the production of the basic components of DNA and RNA—is essential for cell growth and division. In most ...

A team of biochemists at the University of California, Santa Cruz, has developed a faster way to identify molecules in the ...

For the first time, the structure of a DNA enzyme complex implicated in infertility and cancer has been obtained using cryo-electron microscopy (cryo-EM). A collaboration of researchers, led by ...