An altered structure that 'mimics' the active form of BRAF Around half of all cancers are associated with dysfunction of the MAPK pathway, a communication system that enables cells to integrate ...

Yale chemists have synthesized a complex, potentially cancer-fighting molecule found in sea sponges discovered off the coast of South Korea. The work, described in the journal Science, sets the stage ...

Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have identified a small molecule that can inhibit a cancer-driving protein long considered impossible to target with drugs - a ...

Scientists have discovered that a rare “mirror-image” version of the amino acid cysteine can dramatically slow the growth of ...

Yale chemists have synthesized a complex, potentially cancer-fighting molecule found in sea sponges discovered off the coast of South Korea. The work, described in the journal Science, sets the stage ...

Researchers at Scripps Research have identified a hidden filamentous architecture inside cellular droplets called biomolecular condensates, a finding that could reshape how scientists design drugs ...

A Florida State University chemist has developed a method to rapidly assemble significantly complex natural molecules with potential for biomedical applications, opening the door for novel drug ...

Rx for Resilience: Curing Burnout in Oncology Through Smarter Workflows and Supportive Practices The review by Hazim et al 1 in this journal outlines ongoing and planned major clinical trials in ...

MIT scientists have achieved the first-ever lab synthesis of verticillin A, a complex fungal compound discovered in 1970. Its delicate structure stalled chemists for decades, despite differing from ...