They found that the N-terminal region of Pil1 and Lsp1 contains an amphipathic helix, a feature common in BAR-domain proteins that helps them bind to membranes. This helix is embedded in the ...

Protein engineering company Lytica Therapeutics ... AMPs typically comprise 15–50 amino acids that form cationic, amphipathic peptides and predominantly act by binding to and disrupting ...

Depending on specific circumstances, adoption of hydrophobic or amphipathic helical structure on binding to the membrane surface may be followed by membrane insertion, resulting in transmembrane ...