Guanfacine belongs to the class of medications known as central alpha 2A-adrenergic receptor agonists. This class of medications generally helps open your blood vessels, which may lower your heart ...

The 'fight or flight' hormone adrenaline — which is produced during times of stress — is an agonist of the β 2-adrenergic receptor (β 2 AR), a G-protein-coupled receptor (GPCR) that mediates ...

The crystal structure of a second G protein–coupled receptor sheds light on these key pharmaceutical targets. In contrast, β2AR and essentially all of the other GPCRs are present at very low ...

The mechanism of action of clonidine in ADHD is not known. Clonidine stimulates alpha 2-adrenergic receptors in the brain, and is not a central nervous system stimulant. <6yrs: not recommended.