Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated ... Kidins220 expression and inhibiting AMPK phosphorylation. Disclaimer: AAAS and EurekAlert!
This activation of MRTF-A led to the downregulation of Kidins220, a protein crucial for AMPK phosphorylation, which is necessary for glycolysis. Furthermore, inhibiting MRTF-A with the compound ...
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