The global organization of the tRNA structure is highly conserved in all forms of life. Prominent features of the tRNA structure, as shown in the figure, include: an acceptor stem with the CCA ...
The opposite end of the folded structure, which is the 3' end of the tRNA, binds to its corresponding amino acid at an attachment site that is also three nucleotides long, invariably CCA.
The study is published in Nature Communications. The scientists used cryo-electron microscopy to decipher the three-dimensional (3D) structure of the RNA polymerase. They shock-froze the RNA ...
The cloverleaf structure is formed by the folding of the single-stranded tRNA molecule, which is typically 73-90 nucleotides long. The key structural features of tRNA include: The specificity of ...
Mutations in tRNA genes or defects in tRNA modifications can lead to various genetic diseases. These alterations can affect the structure and function of tRNA molecules, leading to impaired protein ...