Cushman & Wakefield announced that it has represented J+R Group in the sale of 2525 Main Street, a 143,269-square-foot office ...

Orange County Fire Authority paramedics responded to the location to administer life-saving measures but pronounced the ...

Years before the L.A. fires, Orchard Hills faced a fire of its own — and came out mostly unscathed due to a long ...

UC Irvine Anteaters (23-5, 13-3 Big West) at CSU Fullerton Titans (6-22, 1-15 Big West) Fullerton, California; Thursday, 10 p.m. EST BOTTOM LINE: UC Irvine hits the road against CSU Fullerton aiming ...

A man died after his car hit a curb and overturned in Irvine, near UC Irvine. A possible medical emergency may have caused ...

C.W. Driver Cos. has completed Irvine High School Performing Arts Center, a facility designed to inspire creativity and ...

An Orange County nonprofit organization spent $26.5 million to buy a nearly 70,000-square-foot building at 2400 Barranca Pkwy ...

There’s an arms race in medicine – scientists design drugs to treat lethal bacterial infections, but bacteria can evolve defenses to those drugs, sending the researchers back to square one. In the ...

The Irvine Police Department has released photos of two Romanian nationals who allegedly perpetrated a “jewelry switch scam” in Culverdale, and investigators believe there could be ...

The fourth-ranked University of Hawai‘i men’s volleyball team begins Big West Conference play and a nine-match homestand with ...

The debt-free building at 300 North LaSalle recently underwent $37 million in renovations and has attracted several law firms ...

Four years before the Palisades and Eaton fires ravaged L.A., Irvine braced for a blaze of its own. A bone-dry summer left the landscape parched and primed to ignite as Santa Ana winds roared ...