Baylis is a village in New Salem Township, Pike County, Illinois, United States. The population was 172 at the 2020 census. Baylis is located at 39°43′43″N 90°54′29″W / 39.72861°N 90.90806°W. According to the 2010 census, Baylis has a total area of 0.47 square miles, all land.