Alexandria is a village in Thayer County, Nebraska, United States. The population was 146 at the 2020 census. In the 1840s and 1850s, the Oregon Trail passed through present-day Thayer County, following the Little Blue River through southeastern Nebraska before crossing into the valley of the Platte River. Settlers arrived along the trail in the late 18…Alexandria is a village in Thayer County, Nebraska, United States. The population was 146 at the 2020 census. In the 1840s and 1850s, the Oregon Trail passed through present-day Thayer County, following the Little Blue River through southeastern Nebraska before crossing into the valley of the Platte River. Settlers arrived along the trail in the late 1850s. The first permanent white residents of the county arrived in 1858, settling about two and a half miles south of present-day Alexandria, on the divide between the Little Blue and Big Sandy Creek. In 1859, Isaac Alexander arrived from Kansas with a portable gristmill; he settled on Big Sandy Creek, where he built a log cabin and stockade.
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